Medisse - Medical technology

Technology

Medisse's lead product is the FlexiSurge® Adhesion Barrier – an adhesion prevention film. This resorbable implant is based on Medisse's novel Poly(1,3-Trimethlene Carbonate) or  PTMC – polymer platform, which has passed all biocompatibility requirements ISO 10933-1:2009. Its unique properties include its uniform and therefore, advantageous surface degradation process after implantation. Furthermore, it is easy to handle during the application due to its transparency (visibility of the surgical site undisturbed) and high flexibility (making it very pliable to the underlying tissue).

  • Surface degradation – the thickness of the material gradually reduces, rather than breaking up into multiple uncontrollable bits during the resorption period
  • Enzymatic Degradation – it only degrades in the body due to the presence of enzymes
  • Hydrophobic – it can be used both in dry and wet environments
  • Acid Resistant – it neither affects nor is affected by the underlying PH value
  • Easy Handling – the material is transparent and highly flexible
  • Creep Resistant – it is form-stable

 

Due to its surface erosion resorption profile, there is no burst of degradation products into the body. Because PTMC is a carbonate, no acidic degradation products are released into body. These two features of PTMC networks make it perfectly suited  for use in medical implants. Furthermore, PTMC's mechanical properties only decrease as the thickness of the material decreases and it is expected to cause less tissue reaction than other materials. The total resorption time of a PTMC implant depends on the dimensions and the polymer production conditions. A cross-linked PTMC film with the dimensions 15 mm x 30 mm x 0.1 mm will typically resorb in about 10-12 weeks.

Based on the PTMC technology, Medisse is exploiting a wide range of resorbable implants that can be used in a large number of surgical indications. The list below shows our current product development pipeline, displaying only a small selection of conceivable devices:

  • FlexiSurge® Adhesion Barrier
  • Scleral Buckle
  • Hernia Mesh
  • Staple-line Reinforcement
  • Periodontal Sheet

For further information, please contact Medisse (see Contact).